Juvenile xanthogranuloma - 若年性黄色肉芽腫症
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ドイツの2022年Stiftung Warentestの結果では、ModelDermに対する消費者満足度は有料の遠隔医療相談よりもわずかに低いだけでした。
ドイツの2022年Stiftung Warentestの結果では、ModelDermに対する消費者満足度は有料の遠隔医療相談よりもわずかに低いだけでした。
relevance score : -100.0%
ReferencesJuvenile xanthogranuloma (JXG) は比較的一般的な疾患であり、小児で最も頻繁に見られる non‑Langerhans cell histiocytic disorder の一つです。症例の約 75 % で病変は生後 1 年以内に出現し、患者の 15 %～20 %以上は出生時から病変を有しています。成人ではまれですが、JXG は通常 20 代後半から 30 代に最も多く発症し、ほとんどの成人患者は病変が 1 つだけです。臨床的には、主に顔、首、上半身に単一または複数の黄・オレンジ・茶色の硬い隆起またはしこりとして現れます。口腔病変はまれですが、舌の側面や口腔内の他部位に黄色のしこりとして出現し、潰瘍や出血を引き起こすことがあります。皮膚病変は通常症状を伴わず、数年かけて自然に消失する傾向があります。まれですが、皮膚以外で最も一般的な合併症は眼の病変で、次いで肺の病変が続きます。Ocular JXG は通常片方の目にのみ影響し、患者の 0.5 % 未満で発生しますが、眼病変のある患者の約 40 % では診断時に複数の皮膚病変も認められます。
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranulomas (JXGs) はまれな良性疾患であり、non-Langerhans cell histiocytosesという大きなカテゴリに属します。通常、1つ以上の赤色または黄色がかったしこりとして現れ、頭部や頸部に多く見られます。ほとんどのJXGは出生時または生後1年以内に発症します。まれに皮膚以外の部位に及ぶことがあり、文献では眼への影響に注意が必要とされています。一般に皮膚のJXGは自然に消退するため、治療は不要です。
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
眼病変は JXG 患者の最大 10% に認められ、視力に影響を与える可能性があります。皮膚病変は多くの場合自然に消失しますが、眼病変が自然に改善することはほとんどなく、治療が必要です。